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Considering their versatility...
I’ve used spray QDs when faced with
many different situations including, but
not limited to, the following:
•To remove fingerprints, dust, smudges.
•As a waterless wash.
•As an LSP booster.
•As a drying-aid.
•As a Clay lubricant.
•As a primer for buffing pads.
•Etc.
Bob
Assuming OP is talking about QDs only, you can use them as often as you want. Most don’t really add measurable protection that should be solely relied on, but therefore they wont do much in changing the behavior of your sealant.
If you are including spray waxes/sealants in your question (such as WG DG Spritz Sealant; not Detail Spritz) then you can use when the car is clean after a wash, every other wash, etc.