With my BMW, if anything, I have found using Rain-X or similar products causes it to wipe more than is actually necessary. Water beads up more than usual on the glass which affects the sensor as rolls by. Because of this, I think the car senses more water droplets. Most of the time though, the wipers aren't even necessary with a treated windshield so it's rarely an annoyance, but I have no way of controlling the wipe interval so there are times it annoys-- mostly in light rain where the wipe interval can be much longer.
When I first bought the car and drove it 120mi home during numerous downpours/showers/drizzle on the highway with an untreated windshield, the rain sensor timing was always perfect. The much improved visibility using a treated a windshield greatly outweighs the minor annoyance, so I only bring up my experience because someone was asking! I would never drive a car in the rain without any type of treatment, if at all possible, and I travel with Rain-X in a small 1/2oz eye drop bottle and bust it out if necessary on a rental where rain looks possible. Having driven a few untreated cars in bad rain, it is simply dangerous, IMO, the way moisture just clings to the windshield.