As I understand it the nano particles are immersed in solution which stops them from becoming airborne for you to inhale. Now at the point you aerosolize a product you would be wise to use protection. As far as skin I personally wear gloves with almost any chemical nano or not.
Atomizing a nano product, through a spray bottle, was what I was thinking about when I wrote that, and in my mind is a real concern, as is breathing any atomized chemical. As Corey stated, protection would be wise.
The concern for a nano solution soaking through rubber gloves is an "unknown" for me, and it would be nice to see some solid scientific research via lengthy studies, that would indicate whether it's safe or not, even with rubber gloves. Having seen no solid evidence through viable research/studies is why I have concerns there as well.
I realize that that many of the products we use in the detailing industry...there's really no reason to be concerned of soak-through with regard to rubber gloves. However...
...having used just a few industrial degreasers in my time that was once considered safe, did in fact eat through rubber gloves...no matter what brands we tried or how thick they were. They eventually all failed. No nano-particles in these chemicals, just cancer causing agents...which was later discovered...after we had used them both with and without rubber gloves.
(The part about not using rubber gloves didn't seem to matter since the chemicals ate through the materials "all of a sudden". Granted the amount of exposure, via time using a nano-coating or other automotive nano product, is minimal compared to what we were exposed to.)
A couple of those industrial degreasers that we were exposed to was Trichlorothane, and Trichlorethylene if I remember the names correctly. One replaced the other, regardless of the order mentioned, because one was found to cause cancer and later on the other chemical was found to cause the same. Too bad so many of us were at times exposed elbow deep numerous times a day, every day to these chemicals. We were first told they were safe to use. Of course, employers always tell their employees a product is safe.
My point is that this nano technology is relatively new. To my knowledge no known long term studies have been published.
Realize I am not saying, "yay," nor, "nay," condoning using these products, rather, be careful and as Corey said, "wear gloves with almost any chemical nano or not."