I would say yes. Spotters seem to have stronger / better / different chemicals for stepped up performance. Same reason you use a spotter in your laundry...you already know Tide is gonna need some help.
On today's interior which suffered from lots of coffee stains, I used APC 10:1 for the bulk of the carpet, but hit the stubborn spots that didn't budge with Folex. Two problems (general dirt, stains) two approaches worked for me.