In my life, only two instances stuck out and not forgotten. One, I shipped myself some good citrus from Florida. I arrived back in the Midwest-Chicago, but the package was lost an additional 5-6 days, about 2 weeks total and when the box arrived, it was very "soggy", and 1/2 the citrus had rotted. (Yep, wonderful UPS)
Most of the shipment was "Orange-Limes", I think they are called "Calemondin"? Very good on Shellfish I found. Was saddening to say the least, those cannot be found in the Midwest.
But the worst was a rare, expensive and said to be brand spanking new Astro-Physics Traveler 4.1" Telescope, and $4500 of my money was on the line, UPS lost the package!
What should've taken 5 business days from California to Chicago, took 12 business days. I was very lucky that it arrived, and was unscathed. The seller was also wise enough to double-box the shipment. I was pretty upset and worried with that ordeal. Whew!
Weather conditions are sometimes just part of the game in winter in the USA. Cannot be helped, an act of God.