I agree with everything that's been said about pads building up product, needing cleaning, etc.
Cleaning on the fly can work as well. But that only works so well. Eventually you'll need to use pad cleaner (liquid) or take your pads to your mud sink and clean them. Once wet, those pads WILL have to dry before you can use them again.
No all that is just about gunk, spent product, removed/abraded paint and contaminates.
The one true enemy to pads however is heat. Try compounding an entire hood, without stopping, (even in sections and wiping each section as you go) and that pad will almost certainly be ruined. Whether it's closed or open cell will not make a difference, heat will build up INSIDE the pad. Some is from friction on the surface, but quite a bit is from friction between the pad and backing plate.
Do two or three 20" square sections, remove the pad, put the back of it to the back of your hand, or to your cheek. If it's more than just barely warm..... change it! Clean it on the fly, sit in on your cart or to the side, grab another pad and get back to work. With as few as 3, you
might be able to compound an entire vehicle. Just rotate, first in, first out and keep putting the coolest one back on the machine. Better yet to get a minimum of 4 and play it safe.
As you move from compounding to polishing the pad does less work, builds less heat, therefore you need fewer pads.

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