DP WHEEL Glaze is a cleaner wax. With a potent cleaner. Just to let you know that it will remove any sealant you have underneath it. So multiple layers with that product is unnecessary and a waste of time and product.
If you are taking the time to remove the wheels and make a project out of it, I would HIGHLY suggest you use a coating product. As in Optimum Polymer Technology's Opti-Coat 2.0. Or Car Pro CQuartz. These products will last for a very long time and reapplication is unnecessary unless you do something abrasive to remove them.
Because removing the wheels for a product like Poorboys Wheel Sealant or DP Wheel Glaze is really not worth the time it takes to do so. These products have a fairly short life or around a month or 2. Thats not slighting the products, its just stating how much punishment wheels take. Between Heat, abrasion from debris, etching from chemicals (used for road maintenance), and corrosive particles (from brake's dust and debris), its very difficult to make any product last like it would on paint, unless it is an actual coating like another layer or paint (ie: Optimum Opti-coat 2.0).
Also, just to note, the sealant used in Poorboys as well as DP wheel Glaze does not need time to cure like a traditional car sealant like Wolfgang Deep Gloss Paint Sealant. Both of these products can be topped within 30 minutes of there initial application. These are different chemicals than used in car paint sealants. The sealant used in poorboys cures fast. Waiting 24 hours between application is a huge waste of time.
Another great product that nobody mentioned is Prima Wheel armor. This is another cleaner/wax-sealant. And its the easier of the 3 to work with, with better results than the other 2 as well. The poorboys is also super easy to work with, but with no cleaners its important to polish the wheels first and remove all residual tar spots. Making it a 2 step product.
hope that info helps. Just to note, I have a 2011 Audi S4, so I feel your paint about brake dust. after one week of even light driving I get what looks to me to be baked on brake dust. Serious stuff to clean. I used to use P21S wheel gel, as well as DP Wheel cleaner until I got this car. Since I got the Audi, I know no longer use them. I refuse to use something that will force me to do 2 applications. I now use exclusively Sonax Full Effect wheel cleaner. Along with CG maxi Suds or Citrus Wash in the wash bucket with a ton of foam for the brush's.